The Science Behind NAD Decline: CD38, Cellular Drain, and Aging

One of the most important discoveries in modern aging science is the NAD+ deficit. Even with good nutrition and regular exercise, NAD+ levels naturally decline with age, often by as much as 50% between early adulthood and later life. For years, researchers debated why this happens. Was the body simply producing less NAD+, or was something actively accelerating its breakdown?

As research advanced, scientists uncovered a key piece of the puzzle, an enzyme called CD38, which increases with age and acts like a constant drain on NAD+, quietly accelerating cellular energy loss over time.

What is CD38?

CD38 is an enzyme found on the surface of many immune cells. In a healthy, young body, CD38 levels are low. Its job is to help the immune system respond to threats. However, it requires energy to work. Specifically, it is a voracious consumer of NAD+.

The "Inflammaging" Connection

As we age, our bodies experience a state of chronic, low-grade inflammation often called "Inflammaging." This causes our immune system to be constantly, slightly overactive.

• The Trigger: Age-related inflammation signals your cells to produce more CD38.
• The Consumption: As CD38 levels rise, they begin to consume NAD+ at a rapid rate, often faster than your body can produce it.
• The Result: It creates a "Cellular Drain." You might be making NAD+, but CD38 is depleting it before it can reach your mitochondria or PARP repair enzymes.

The NAD+7 Strategy: Fill and Protect

A complete anti-aging strategy cannot just focus on one side of the equation. You need to boost production and minimize waste.

NAD+7 is formulated to address both sides of the coin:

• Boost Production: We use Nicotinamide Riboside (NR) to pour fuel into the tank, stimulating fresh NAD+ production.
• Manage the Drain: Our formula includes powerful polyphenols like Resveratrol and Quercetin. These compounds are scientifically studied for their ability to support a healthy inflammatory response and inhibit CD38 activity, effectively helping to plug the drain.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.